Online Cancer Support Is Available

Online Cancer Support Is Available



Last month, our legal blogger Karen Marshall wrote a post about Picking Your Support Team. Your support team is made with the people that will provide you with the care, support, and information through your journey of cancer treatment. It is important to...

Read More: Online Cancer Support Is Available

#Confusion, #Diagnosis, #Emotions, #Experience, #History, #Latest, #Marshall, #Mesothelioma, #Result, #Survivors, #Thoughts

Famous People Who Battled Mesothelioma

http://www.mybiologica.com/wp-content/uploads/2014/02/a6f0MerlinOlsen-261x300.jpg


Famous People Who Battled Mesothelioma



Mesothelioma is a cancer most often associated with military service and blue-collar professions, but the asbestos-created disease has touched all walks of life. That includes the rich and the famous.
Professional athletes, Olympic gold medalists,...

Read More: Famous People Who Battled Mesothelioma

#Athletes, #Cancer, #Century, #Fame, #Highest, #League, #Mcqueen, #Prairie, #Renowned, #Result, #Studios

Extreme weather caused by climate change decides distribution of insects, study shows

http://feeds.feedburner.com/~r/sciencedaily/top_news/top_science/~4/VPFfxGpHPRc

As climate change is progressing, the temperature of our planet increases. This is particularly important for the large group of animals that are cold-blooded (ectothermic), including insects. Their body temperature is ultimately determined by the ambient temperature, and the same therefore applies to the speed and efficiency of their vital biological processes.But is it changes in average temperature or frequency of extreme temperature conditions that have the greatest impact on species distribution? This was the questions that a group of Danish and Australian researchers decided to examine in a number of insect species.Johannes Overgaard, Department of Bioscience, Aarhus University, Denmark, Michael R. Kearney and Ary A. Hoffmann, Melbourne University, Australia, recently published the results of these studies in the journal Global Change Biology. The results demonstrate that it is especially the extreme temperature events that define the distribution of both tropical and temperate species. Thus climate change affects ectotermic animals primarily because more periods of extreme weather are expected in the future.Fruit flies were modeledThe researchers examined 10 fruit fly species of the genus Drosophila adapted to tropical and temperate regions of Australia. First they examined the temperatures for which the species can sustain growth and reproduction, and then they found the boundaries of tolerance for hot and cold temperatures.”This is the first time ever where we have been able to compare the effects of extremes and changes in average conditions in a rigorous manner across a group of species,” mentions Ary Hoffmann.Based on this knowledge and knowledge of the present distribution of the 10 species they then examined if distribution was correlated to the temperatures required for growth and reproduction or rather limited by their tolerance to extreme temperature conditions.”The answer was unambiguous: it is the species’ tolerance to very cold or hot days that define their present distribution,” says Johannes Overgaard.It is therefore the extreme weather events, such as heat waves or extremely cold conditions, which costs the insects their life, not an increase in average temperature.Drastic changes in storeWith this information in hand, the researchers could then model how distributions are expected to change if climate change continues for the next 100 years.Most terrestrial animals experience temperature variation on both daily and seasonal time scale, and they are adapted to these conditions. Thus, for a species to maintain its existence under varying temperature conditions there are two simple conditions that must be met. …


Read More: Extreme weather caused by climate change decides distribution of insects, study shows

#Alternative-Medicine, #Australia, #Decades, #Events, #Health, #Kilometers, #Melbourne, #Planet, #Result, #Species, #Study, #University

Dangers of ... sitting? Regardless of exercise, too much sedentary time is linked to major disability after 60

http://feeds.feedburner.com/~r/sciencedaily/living_well/~4/5_FkhETjBec

If you’re 60 and older, every additional hour a day you spend sitting is linked to doubling the risk of being disabled — regardless of how much moderate exercise you get, reports a new Northwestern Medicine study.The study is the first to show sedentary behavior is its own risk factor for disability, separate from lack of moderate vigorous physical activity. In fact, sedentary behavior is almost as strong a risk factor for disability as lack of moderate exercise.If there are two 65-year-old women, one sedentary for 12 hours a day and another sedentary for 13 hours a day, the second one is 50 percent more likely to be disabled, the study found.”This is the first time we’ve shown sedentary behavior was related to increased disability regardless of the amount of moderate exercise,” said Dorothy Dunlop, professor of medicine at Northwestern University Feinberg School of Medicine and lead author of the study. “Being sedentary is not just a synonym for inadequate physical activity.”Disability affects more than 56 million Americans. It’s defined by limitations in being able to do basic activities such as eating, dressing or bathing oneself, getting in and out of bed and walking across a room. Disability increases the risk of hospitalization and institutionalization and is a leading source of health care costs, accounting for $1 in $4 spent.The study will be published February 19 in the Journal of Physical Activity & Health.The finding — that being sedentary was almost as strong a risk factor for disability as lack of moderate vigorous activity — surprised Dunlop.”It means older adults need to reduce the amount of time they spend sitting, whether in front of the TV or at the computer, regardless of their participation in moderate or vigorous activity,” she said.The study focused on a sample of 2,286 adults aged 60 and older from the National Health and Nutrition Examination Survey. It compared people in similar health with the same amount of moderate vigorous activity. Moderate activity is walking briskly, as if you are late to an appointment.The participants wore accelerometers from 2002 to 2005 to measure their sedentary time and moderate vigorous physical activity. The accelerometer monitoring is significant because it is objective. The older and heavier people are, the more they tend to overestimate their physical activity. Previous research indicated a relationship between sedentary behavior and disability but it was based on self-reports and, thus, couldn’t be verified.Because the study examines data at one point in time, it doesn’t definitively determine sedentary behavior causes disability. …


Read More: Dangers of ... sitting? Regardless of exercise, too much sedentary time is linked to major disability after 60

#Activity, #Alternative-Medicine, #Alzheimer, #Disability, #Ecology, #Nutrition, #Physical, #Professor, #Result, #Science, #Sedentary, #University

Still no Field Sobriety Test for Marijuana

http://www.mybiologica.com/wp-content/uploads/2014/02/c62cdoesusingmarijuanacausecarcrashes.jpg

Photo Credit How do police identify a stoned driver?The standard field sobriety test involves having a driver walk heel to toe, turn on one foot and walk back heel to toe and stand on one leg for 30 seconds. This is said to catch almost 90% of drunk drivers – but does it do the same for stoned drivers?According to an article published in the New York Times it does not. In fact, only 30% of stoned drivers with THC in their systems fail these motor skills and the rates are even lower for veteran stoners who are used to being high.Crafting a standard field sobriety test that works for marijuana is becoming increasingly important as states legalize its recreational and medical use. Still little…


Read More: Still no Field Sobriety Test for Marijuana

#Colorado, #Drivers, #Driving-Under-Influence, #Driving-While-Stoned, #Institute, #Manager, #Result, #Thc, #Timesitdoes

What to Say When Your Friend or Loved One Tells You They Have Cancer

What to Say When Your Friend or Loved One Tells You They Have Cancer



A cancer diagnosis is a life changing experience with many challenges.  One of the difficulties with cancer is telling your friends and family.  Knowing that you have a support network there to help you can alleviate some b...

Read More: What to Say When Your Friend or Loved One Tells You They Have Cancer

#Age, #Appointments, #Cancer, #Challenges, #Chores, #Confidentiality, #Friends, #Groceries, #Medical, #Result, #Rule

Clutter cutter: Computer modeling used to understand how messy cells contribute to cancer

http://feeds.feedburner.com/~r/sciencedaily/top_news/top_health/~4/BfE-IJRw804

Life can be messy at all scales, requiring different organizational strategies — from cleaning the house, to removing damaged or expired cells from the body to avoid cancer progression.In a messy house, people use computers to manage paper and photo clutter; companies use computer systems to track their inventory. Now a team of researchers at Vanderbilt University in Nashville, Tenn., is taking a similar approach to cell-molecular inventory control for cancer. They have created computer models, using their programming framework (PySB), which enable them to explore the complex biochemical processes that drive cancer growth.”Our hypothesis is that understanding how the cell uses their protein inventory will lead to understanding why cells dysregulate and become carcinogenic. We expect model outputs will lead to novel, targeted cancer therapies — possibly by 2019,” explained researcher Carlos F. Lopez, who will present the work at the 58th annual Biophysical Society Meeting in San Francisco, Feb.15-19.Lopez is interested in understanding how cells in multicellular organisms engage programmed cell death — so-called “cell suicide” — for cellular removal. It is a natural part of many cells’ life cycle.When cancer cells avoid programmed cell death, uncontrolled growth fuels tumor progression. The Vanderbilt team expects their computer models to identify what goes wrong in these cases, at a speed and scale never before possible. Lopez noted: “We are bridging the nanoscale molecular-level biochemical interactions with the macroscale cancer tumor outcomes, which is a huge range in scales. Most people don’t realize this, but molecular chemical reactions at the nanometer and nanosecond level affect things that happen at the timescale level of years — nine orders of magnitude in space and time! For comparison, a nanosecond is to a second like a second is to one century.”Rather than listing the cellular biochemical reactions by hand, PySB enables the researchers to “write” the biochemical cellular processes as computer programs. …


Read More: Clutter cutter: Computer modeling used to understand how messy cells contribute to cancer

#Agriculture, #Alzheimer, #Body, #Carlos, #Cell, #Inventory, #Lopez, #Processes, #Protein, #Researchers, #Result, #University

Mavis Nye | Survivor Insight Series

Mavis Nye | Survivor Insight Series



Ben Leer spoke with Mavis Nye for this post contributing to The Mesothelioma Center’s Survivor Insight Series. Mavis is a survivor and fighter of pleural Mesothelioma. Mavis joins us today to share her story.
What were the events that led up to your...

Read More: Mavis Nye | Survivor Insight Series

#Cancer, #Chatham, #Health, #Issues, #Medway, #Mesothelioma, #Result, #Survivor, #Television

Choosing the Right Wheelchair for a Loved One with Mesothelioma

http://www.mybiologica.com/wp-content/uploads/2014/02/3ae5caregiver-controlled-wheelchair.jpg


Choosing the Right Wheelchair for a Loved One with Mesothelioma



Pushing someone in a wheelchair may appear to be an easy task, but there is more to this than meets the eye. I learned this when caregiving for my husband during his mesothelioma illness. When the need arose for a wheelchair, I...

Read More: Choosing the Right Wheelchair for a Loved One with Mesothelioma

#Chair, #Companion, #Electric, #Manual, #Mesothelioma, #Quality, #Result, #Wheel, #Wheelchairs, #Wheels

Why one prostate cancer patient traveled across the country for proton therapy

http://www.mybiologica.com/wp-content/uploads/2014/02/2e5adougneal21814.jpg


Why one prostate cancer patient traveled across the country for proton therapy




via Cancerwise | Cancer blog from MD Anderson Cancer Center:
Doug Neal didn’t waste a moment. After his prostate cancer diagnosis, he started researching, determined to find the best treatment. He talked...

Read More: Why one prostate cancer patient traveled across the country for proton therapy

#Career, #Choice, #Commercial, #Fisherman, #Particles, #Prostate, #Prostatecancer, #Proton-Therapy, #Result, #Therapy, #Treatment

It’s alive! Bacteria-filled liquid crystals could improve biosensing

http://feeds.feedburner.com/~r/sciencedaily/top_news/top_health/~4/EOvk6Qdu_gw

Plop living, swimming bacteria into a novel water-based, nontoxic liquid crystal and a new physics takes over. The dynamic interaction of the bacteria with the liquid crystal creates a novel form of soft matter: living liquid crystal.The new type of active material, which holds promise for improving the early detection of diseases, was developed by a research collaboration based at Ohio’s Kent State University and Illinois’ Argonne National Laboratory. The team will present their work at the 58th annual Biophysical Society Meeting, held in San Francisco, Feb.15-19.As a biomechanical hybrid, living liquid crystal moves and reshapes itself in response to external stimuli. It also stores energy just as living organisms do to drive its internal motion. And it possesses highly desirable optical properties. In a living liquid crystal system, with the aid of a simple polarizing microscope, you can see with unusual clarity the wake-like trail stimulated by the rotation of bacterial flagella just 24-nanometers thick, about 1/4000th the thickness of an average human hair.You can also control and guide active movements of the bacteria by manipulating variables such as oxygen availability, temperature or surface alignment, thus introducing a new design concept for creating microfluidic biological sensors. Living liquid crystal provides a medium to amplify tiny reactions that occur at the micro- and nano-scales — where molecules and viruses interact — and to also easily optically detect and analyze these reactions. That suits living liquid crystal to making sensing devices that monitor biological processes such as cancer growth, or infection. Such microfluidic technology is of increasing importance to biomedical sensing as a means of detecting disease in its earliest stages when it is most treatable, and most cost-effectively managed.”As far as we know, these things have never been done systematically as we did before in experimental physics,” explained Shuang Zhou, a Ph.D. candidate at Ohio’s Kent State University. …


Read More: It’s alive! Bacteria-filled liquid crystals could improve biosensing

#Argonnenational, #Bacteria, #Biophysical, #Diseases, #Dynamic, #Health, #Living, #Matter, #Result, #State, #Stateuniversity, #Work

Veterans Video: Asbestos Exposure in the U.S. Navy

http://img.youtube.com/vi/9hgWioRqHbQ/0.jpg


Veterans Video: Asbestos Exposure in the U.S. Navy





Here’s the latest installment in our Veterans video series. It is titled, “Asbestos Exposure in the Navy.”
Some of this is covered in the video, but here are a few details: Roughly one-third of those diagnosed with...

Read More: Veterans Video: Asbestos Exposure in the U.S. Navy

#Collar, #Craft, #Exposure, #Mesothelioma, #Military, #Navy, #Result, #Series, #Veterans, #World

Naturally Occurring Asbestos and What You Can Do To Avoid It

http://www.mybiologica.com/wp-content/uploads/2014/02/8899Dr-Brenda-Buck.jpeg-600x399.jpg


Naturally Occurring Asbestos and What You Can Do To Avoid It













Image Source: Dr. Buck & colleague examine rocks for NOA

The recent discovery of windblown asbestos dust near Las Vegas, NV has drawn new attention to the phenomenon of naturally occurring asbestos (NOA). Dr. Brenda...

Read More: Naturally Occurring Asbestos and What You Can Do To Avoid It

#Asbestos-Near-Las-Vegas, #Geological, #Industrial, #Mesothelioma, #Minerals, #Processes, #Purposes, #Result, #Southern, #Substance, #Superfund

How evolution shapes the geometries of life

http://feeds.feedburner.com/~r/sciencedaily/top_news/top_science/~4/iA1jf17zg24

Why does a mouse’s heart beat about the same number of times in its lifetime as an elephant’s, although the mouse lives about a year, while an elephant sees 70 winters come and go? Why do small plants and animals mature faster than large ones? Why has nature chosen such radically different forms as the loose-limbed beauty of a flowering tree and the fearful symmetry of a tiger?These questions have puzzled life scientists since ancient times. Now an interdisciplinary team of researchers from the University of Maryland and the University of Padua in Italy propose a thought-provoking answer based on a famous mathematical formula that has been accepted as true for generations, but never fully understood. In a paper published the week of Feb. 17, 2014 in the Proceedings of the National Academy of Sciences, the team offers a re-thinking of the formula known as Kleiber’s Law. Seeing this formula as a mathematical expression of an evolutionary fact, the team suggests that plants’ and animals’ widely different forms evolved in parallel, as ideal ways to solve the problem of how to use energy efficiently.If you studied biology in high school or college, odds are you memorized Kleiber’s Law: metabolism equals mass to the three-quarter power. This formula, one of the few widely held tenets in biology, shows that as living things get larger, their metabolisms and their life spans increase at predictable rates. Named after the Swiss biologist Max Kleiber who formulated it in the 1930s, the law fits observations on everything from animals’ energy intake to the number of young they bear. It’s used to calculate the correct human dosage of a medicine tested on mice, among many other things.But why does Kleiber’s Law hold true? …


Read More: How evolution shapes the geometries of life

#Alzheimer, #Evolution, #Phenomena, #Physics, #Plant, #Plants, #Result, #Sciences, #Space, #Switzerland, #Team, #Tree

Understanding (and Signing) the Mesothelioma Attorney-Client Agreement

Understanding (and Signing) the Mesothelioma Attorney-Client Agreement



In an earlier post we discussed how communication is vital to the attorney-client relationship. Once you’ve selected a qualified attorney who communicates clearly with you and makes you feel comfortable, it’s...

Read More: Understanding (and Signing) the Mesothelioma Attorney-Client Agreement

#Agreement, #Attorney, #Case, #Contingency, #Discovery, #Mesothelioma, #Result, #Signature

Veterans Video: The VA Benefits Process Is Not Hard with Some Help

http://img.youtube.com/vi/sI3OOIbEdnw/0.jpg


Veterans Video: The VA Benefits Process Is Not Hard with Some Help





The fifth in our series of veterans videos (below) is about VA benefits process. Some veterans tend to believe that: The VA doesn’t want to hand out benefits. The VA process doesn’t make any sense. The process...

Read More: Veterans Video: The VA Benefits Process Is Not Hard with Some Help

#Groups, #Heck, #Industry, #Insurance, #Madness, #Members, #Mesothelioma, #Result

Lou Williams | Survivor Insight Series

http://www.mybiologica.com/wp-content/uploads/2014/02/e5e5shutterstock_61481899-150x150.jpg


Lou Williams | Survivor Insight Series



Louise Williams has been affected by mesothelioma since the diagnosis of her father. He developed the disease through occupational exposure to asbestos.
She came into contact with the deadly mineral several times in her life over the span of several...

Read More: Lou Williams | Survivor Insight Series

#Australia, #Childhood, #Constant, #Diseases, #Melbourne, #Mesothelioma, #Result, #Stories-From-Survivors, #Substance, #Williams

Responding to potential asteroid redirect mission targets

http://feeds.feedburner.com/~r/sciencedaily/top_news/top_science/~4/3l8C3oGKxxQ

One year ago, on Feb. 15, 2013, the world was witness to the dangers presented by near-Earth Objects (NEOs) when a relatively small asteroid entered Earth’s atmosphere, exploding over Chelyabinsk, Russia, and releasing more energy than a large atomic bomb. Tracking near-Earth asteroids has been a significant endeavor for NASA and the broader astronomical community, which has discovered 10,713 known near-Earth objects to date. NASA is now pursuing new partnerships and collaborations in an Asteroid Grand Challenge to accelerate NASA’s existing planetary defense work, which will help find all asteroid threats to human population and know what to do about them. In parallel, NASA is developing an Asteroid Redirect Mission (ARM) — a first-ever mission to identify, capture and redirect an asteroid to a safe orbit of Earth’s moon for future exploration by astronauts in the 2020s.ARM will use capabilities in development, including the new Orion spacecraft and Space Launch System (SLS) rocket, and high-power Solar Electric Propulsion. All are critical components of deep-space exploration and essential to meet NASA’s goal of sending humans to Mars in the 2030s. The mission represents an unprecedented technological feat, raising the bar for human exploration and discovery, while helping protect our home planet and bringing us closer to a human mission to one of these intriguing objects.NASA is assessing two concepts to robotically capture and redirect an asteroid mass into a stable orbit around the moon. In the first proposed concept, NASA would capture and redirect an entire very small asteroid. In the alternative concept, NASA would retrieve a large, boulder-like mass from a larger asteroid and return it to this same lunar orbit. In both cases, astronauts aboard an Orion spacecraft would then study the redirected asteroid mass in the vicinity of the moon and bring back samples.Very few known near-Earth objects are ARM candidates. …


Read More: Responding to potential asteroid redirect mission targets

#Atomic, #Defense, #Nasa, #Objectprogram, #Orbit, #Planet, #Program, #Result, #Space

New research reinforces danger of drinking alcohol while pregnant

http://feeds.feedburner.com/~r/sciencedaily/living_well/~4/xUl0Fs-szv8

Women who drink alcohol at moderate or heavy levels in the early stages of their pregnancy might damage the growth and function of their placenta — the organ responsible for supplying everything that a developing infant needs until birth — research at The University of Manchester shows.Placentas studied in a laboratory environment showed that drinking alcohol at moderate (2/3 standard drinks) to high (4-6 standard drinks) rates reduced the cell growth in a woman’s placenta.The research, published in the journal PLoS One and funded by the British Medical Association, investigated the effect of alcohol and its major toxic breakdown product, acetaldehyde, had on the placenta in the first few weeks — a period essential for normal development where three primary germ cell layers in the very early infant develop into internal organs.While placental cell growth was reduced at mid and heavy drinking levels, the cells that ensure the placenta attaches to the mother were unaffected. Alcohol at very low concentrations (1-2units, equal to half or one standard drink) did not have any effect on growth or function. Scientists also found alcohol at moderate to heavy levels reduced the transport of an important amino acid — known as taurine — from mother to baby via the placenta.Taurine is vital for brain and physiological development. However, acetaldehyde did not have any effect on the transportation of taurine suggesting alcohol is the main culprit. Reduced taurine has been shown to have negative effects on behaviour and physical development, so this might explain why some neurological symptoms are seen in children of alcoholic mothers, the researchers conclude.Sylvia Lui, from the Tommy’s Maternal and Fetal Health Research Centre based at The University of Manchester who carried out the research, said: “Alcohol and acetaldehyde are known to be toxic at high levels, but these results clearly show that levels easily achieved in a normal population have specific effects in the placenta.”Placental growth is reduced in comparison to non-exposed placentas, suggesting that in the long-term, there could be consequences to how much support the infant receives from the placenta during the rest of the pregnancy after this exposure.”Dr Clare Tower, consultant obstetrician at Saint Mary’s Hospital part of Central Manchester University Hospitals NHS Foundation Trust, said: “Though low levels of alcohol did not have a harmful effect, moderate to high levels were damaging. The safest clinical advice would be to agree with the current Royal College of Obstetrics and Gynaecology guidelines and abstain.This is because UK studies show that there is still a lot of confusion in the perception of what alcohol ‘units’ are, as well as a lack of accurate self-monitoring of drinking levels.Professor John Aplin, Professor of Reproductive Biomedicine in the Tommy’s Maternal and Fetal Health Research Centre at the University, said “This research also suggests that women who are trying to conceive should not drink as the damage caused by alcohol can happen very early on in pregnancy — perhaps before a woman knows she is pregnant.”Jane Brewin, Chief Executive of baby charity Tommy’s, said: “It can often be a few weeks before a woman discovers she’s pregnant, and this research shows that moderate drinking during those vital first weeks can have a big impact on the development of the baby.”Many pregnancies are unplanned, but for those actively planning a family this research raises questions about whether women should consider their alcohol intake even before they fall pregnant.”Story Source:The above story is based on materials provided by Manchester University. Note: Materials may be edited for content and length.


Read More: New research reinforces danger of drinking alcohol while pregnant

#Alcohol, #Alternative-Medicine, #Chief, #Ecology, #Executive, #Major, #Result, #Royal, #Story

Passive smoking impairs children"s responses to asthma treatment

http://feeds.feedburner.com/~r/sciencedaily/living_well/~4/MeBxYubk7CI

Children exposed to cigarette smoke at home have lower levels of an enzyme that helps them respond to asthma treatment, a study has found.Passive smoking is known to worsen asthma symptoms in children and impair their response to inhaled steroid treatment, but how this effect occurs was not known.Researchers at Imperial College London found that children with severe asthma with a parent who smokes at home have lower levels of the enzyme HDAC2 compared with those whose parents don’t smoke. HDAC2 is required for steroids to exert their beneficial anti-inflammatory effects in asthma.The findings are reported in the journal Chest.Professor Peter Barnes FRS, from the National Heart and Lung Institute at Imperial College London, said: “The mechanism we’ve identified makes children less sensitive to inhaled steroid treatment, so they suffer more symptoms and might have to take higher doses of steroids, which may lead to side effects.”These findings underline the importance of legislation aimed at protecting children from being exposed to cigarette smoke. Restricting smoking in cars is a positive step, but the same should be applied in homes.”Over a million children in the UK have asthma. Steroid treatments, usually taken using inhalers, are given to prevent asthma attacks, but for many patients, they aren’t completely effective.The Imperial researchers studied 19 children with severe asthma receiving treatment at Royal Brompton Hospital in London. Nine had parents who smoked at home and 10 were from non-smoking households.Cells from the lungs of children exposed to second-hand smoke had about half the levels of HDAC2 enzymes as those from children from non-smoking families.”Children with asthma who are passively exposed to cigarette smoke have the same molecular abnormalities that lead to steroid resistance as adults who actively smoke,” said Professor Barnes. “The mechanism we’ve identified will be a target for new treatments to help children with severe asthma.”Story Source:The above story is based on materials provided by Imperial College London. The original article was written by Sam Wong. Note: Materials may be edited for content and length.


Read More: Passive smoking impairs children"s responses to asthma treatment

#Alzheimer, #Cancer, #College, #Enzyme, #King, #Peterbarnes, #Restricting, #Result, #Royalbrompton, #Story